ACE inhibitor is a effective, easily accepted anti-hypertensive drug of which side effects are infrequent and not serious.
We observed 44 patients who had been treated with once-daily, low dose captopril for 12 weeks. The dose of captopril was 25 or 50mg per day.
Among 44 patients. There were 28 patients(63.6%) whose diastolic blood pressure was lowereed below 90mmHg. But among nother 16patients, 14 patients should have been treated with larger amounts of captopril and 2 patients shuld have been
changed to
other drugs for the purpose of lowering the distolic pressure below 90mmHg.
In order to find the factors that influenced the control of hypertension, we investigated several factors, such as the patient's age, sex, the period of hypertension, the amount of alchol intake, Body mass Index(BMI), and the level of initial
blood
pressure, but we didn't find any specific factors that thd influenced the difference between the controlled group and the non-controlled group sho had taken once-daily, low dose captopril(p>0.05).
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